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Combination peptide immunotherapy based on T‐cell epitope mapping reduces allergen‐specific IgE and eosinophilia in allergic airway inflammation

Peptide immunotherapy using soluble peptides containing allergen‐derived immunodominant T‐cell epitopes holds therapeutic promise for allergic asthma. Previous studies in BALB/c mice using the immunodominant peptide epitope of chicken ovalbumin (p323–339) have been unable to demonstrate therapeutic...

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Detalhes bibliográficos
Main Authors: Mackenzie, Karen J., Fitch, Paul M., Leech, Melanie D., Ilchmann, Anne, Wilson, Claire, McFarlane, Amanda J., Howie, Sarah E.M., Anderton, Stephen M., Schwarze, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573279/
https://ncbi.nlm.nih.gov/pubmed/23113712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12032
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