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Combination peptide immunotherapy based on T‐cell epitope mapping reduces allergen‐specific IgE and eosinophilia in allergic airway inflammation

Peptide immunotherapy using soluble peptides containing allergen‐derived immunodominant T‐cell epitopes holds therapeutic promise for allergic asthma. Previous studies in BALB/c mice using the immunodominant peptide epitope of chicken ovalbumin (p323–339) have been unable to demonstrate therapeutic...

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Bibliografiske detaljer
Main Authors: Mackenzie, Karen J., Fitch, Paul M., Leech, Melanie D., Ilchmann, Anne, Wilson, Claire, McFarlane, Amanda J., Howie, Sarah E.M., Anderton, Stephen M., Schwarze, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573279/
https://ncbi.nlm.nih.gov/pubmed/23113712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12032
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