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Recognition of a High Affinity MHC Class I-Restricted Epitope of Myelin Oligodendrocyte Glycoprotein by CD8(+) T Cells Derived from Autoantigen-Deficient Mice
CD4(+) T cells have a well-defined pathogenic role in experimental autoimmune encephalomyelitis, the rodent model of multiple sclerosis (MS), yet CD8(+) T cells are commonly found in MS lesions. To determine whether immunological tolerance might impact differently on CD4(+) versus CD8(+) T cells, we...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342349/ https://ncbi.nlm.nih.gov/pubmed/22566807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2011.00017 |
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