Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3‐ITD‐driven acute myeloid leukemia

Por Lopez‐Reyes, Rosa G., Quinet, Grégoire, Gonzalez‐Santamarta, Maria, Larrue, Clément, Sarry, Jean‐Emmanuel, Rodriguez, Manuel S.
Publicado no FEBS Open Bio (2020)

Oncogenic KIT mutations induce STAT3-dependent autophagy to support cell proliferation in acute myeloid leukemia

Por Larrue, Clément, Heydt, Quentin, Saland, Estelle, Boutzen, Héléna, Kaoma, Tony, Sarry, Jean-Emmanuel, Joffre, Carine, Récher, Christian
Publicado no Oncogenesis (2019)

Dendrogenin A Synergizes with Cytarabine to Kill Acute Myeloid Leukemia Cells In Vitro and In Vivo

Por Serhan, Nizar, Mouchel, Pierre-Luc, de Medina, Philippe, Segala, Gregory, Mougel, Aurélie, Saland, Estelle, Rives, Arnaud, Lamaziere, Antonin, Despres, Gaëtan, Sarry, Jean-Emmanuel, Larrue, Clément, Vergez, François, Largeaud, Laetitia, Record, Michel, Récher, Christian, Silvente-Poirot, Sandrine, Poirot, Marc
Publicado no Cancers (Basel) (2020)

CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia

Por Bertoli, Sarah, Boutzen, Helena, David, Laure, Larrue, Clément, Vergez, François, Fernandez-Vidal, Anne, Yuan, Lingli, Hospital, Marie-Anne, Tamburini, Jérôme, Demur, Cécile, Delabesse, Eric, Saland, Estelle, Sarry, Jean-Emmanuel, Galcera, Marie-Odile, Mas, Véronique Mansat-De, Didier, Christine, Dozier, Christine, Récher, Christian, Manenti, Stéphane
Publicado no Oncotarget (2015)

Dexamethasone in hyperleukocytic acute myeloid leukemia

Por Bertoli, Sarah, Picard, Muriel, Bérard, Emilie, Griessinger, Emmanuel, Larrue, Clément, Mouchel, Pierre Luc, Vergez, François, Tavitian, Suzanne, Yon, Edwige, Ruiz, Jean, Delabesse, Eric, Luquet, Isabelle, Linares, Laetitia Karine, Saland, Estelle, Carroll, Martin, Danet-Desnoyers, Gwenn, Sarry, Audrey, Huguet, Françoise, Sarry, Jean Emmanuel, Récher, Christian
Publicado no Haematologica (2018)

Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites

Por Bosc, Claudie, Broin, Nicolas, Fanjul, Marjorie, Saland, Estelle, Farge, Thomas, Courdy, Charly, Batut, Aurélie, Masoud, Rawand, Larrue, Clément, Skuli, Sarah, Espagnolle, Nicolas, Pagès, Jean-Christophe, Carrier, Alice, Bost, Frédéric, Bertrand-Michel, Justine, Tamburini, Jérôme, Récher, Christian, Bertoli, Sarah, Mansat-De Mas, Véronique, Manenti, Stéphane, Sarry, Jean-Emmanuel, Joffre, Carine
Publicado no Nat Commun (2020)

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

Por Jacque, Nathalie, Ronchetti, Anne Marie, Larrue, Clément, Meunier, Godelieve, Birsen, Rudy, Willems, Lise, Saland, Estelle, Decroocq, Justine, Maciel, Thiago Trovati, Lambert, Mireille, Poulain, Laury, Hospital, Marie Anne, Sujobert, Pierre, Joseph, Laure, Chapuis, Nicolas, Lacombe, Catherine, Moura, Ivan Cruz, Demo, Susan, Sarry, Jean Emmanuel, Recher, Christian, Mayeux, Patrick, Tamburini, Jérôme, Bouscary, Didier
Publicado no Blood (2015)

Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells

Por Larrue, Clément, Guiraud, Nathan, Mouchel, Pierre-Luc, Dubois, Marine, Farge, Thomas, Gotanègre, Mathilde, Bosc, Claudie, Saland, Estelle, Nicolau-Travers, Marie-Laure, Sabatier, Marie, Serhan, Nizar, Sahal, Ambrine, Boet, Emeline, Mouche, Sarah, Heydt, Quentin, Aroua, Nesrine, Stuani, Lucille, Kaoma, Tony, Angenendt, Linus, Mikesch, Jan-Henrik, Schliemann, Christoph, Vergez, François, Tamburini, Jérôme, Récher, Christian, Sarry, Jean-Emmanuel
Publicado no Nat Commun (2021)

Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia

Por Boutzen, Héléna, Saland, Estelle, Larrue, Clément, de Toni, Fabienne, Gales, Lara, Castelli, Florence A., Cathebas, Mathilde, Zaghdoudi, Sonia, Stuani, Lucille, Kaoma, Tony, Riscal, Romain, Yang, Guangli, Hirsch, Pierre, David, Marion, De Mas-Mansat, Véronique, Delabesse, Eric, Vallar, Laurent, Delhommeau, François, Jouanin, Isabelle, Ouerfelli, Ouathek, Le Cam, Laurent, Linares, Laetitia K., Junot, Christophe, Portais, Jean-Charles, Vergez, François, Récher, Christian, Sarry, Jean-Emmanuel
Publicado no J Exp Med (2016)

Dendrogenin A drives LXR to trigger lethal autophagy in cancers

Por Segala, Gregory, David, Marion, de Medina, Philippe, Poirot, Mathias C., Serhan, Nizar, Vergez, François, Mougel, Aurelie, Saland, Estelle, Carayon, Kevin, Leignadier, Julie, Caron, Nicolas, Voisin, Maud, Cherier, Julia, Ligat, Laetitia, Lopez, Frederic, Noguer, Emmanuel, Rives, Arnaud, Payré, Bruno, Saati, Talal al, Lamaziere, Antonin, Despres, Gaëtan, Lobaccaro, Jean-Marc, Baron, Silvere, Demur, Cecile, de Toni, Fabienne, Larrue, Clément, Boutzen, Helena, Thomas, Fabienne, Sarry, Jean-Emmanuel, Tosolini, Marie, Picard, Didier, Record, Michel, Récher, Christian, Poirot, Marc, Silvente-Poirot, Sandrine
Publicado no Nat Commun (2017)

Chemotherapy Resistant Human Acute Myeloid Leukemia Cells are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

Por Farge, Thomas, Saland, Estelle, de Toni, Fabienne, Aroua, Nesrine, Hosseini, Mohsen, Perry, Robin, Bosc, Claudie, Sugita, Mayumi, Stuani, Lucille, Fraisse, Marine, Scotland, Sarah, Larrue, Clément, Boutzen, Héléna, Féliu, Virginie, Nicolau-Travers, Marie-Laure, Cassant-Sourdy, Stéphanie, Broin, Nicolas, David, Marion, Serhan, Nizar, Sarry, Audrey, Tavitian, Suzanne, Kaoma, Tony, Vallar, Laurent, Iacovoni, Jason, Linares, Laetitia K., Montersino, Camille, Castellano, Rémy, Griessinger, Emmanuel, Collette, Yves, Duchamp, Olivier, Barreira, Yara, Hirsch, Pierre, Palama, Tony, Gales, Lara, Delhommeau, François, Garmy-Susini, Barbara, Portais, Jean-Charles, Vergez, François, Selak, Mary A., Danet-Desnoyers, Gwenn, Carroll, Martin, Récher, Christian, Sarry, Jean-Emmanuel
Publicado no Cancer Discov (2017)

Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia

Por Stuani, Lucille, Sabatier, Marie, Saland, Estelle, Cognet, Guillaume, Poupin, Nathalie, Bosc, Claudie, Castelli, Florence A., Gales, Lara, Turtoi, Evgenia, Montersino, Camille, Farge, Thomas, Boet, Emeline, Broin, Nicolas, Larrue, Clément, Baran, Natalia, Cissé, Madi Y., Conti, Marc, Loric, Sylvain, Kaoma, Tony, Hucteau, Alexis, Zavoriti, Aliki, Sahal, Ambrine, Mouchel, Pierre-Luc, Gotanègre, Mathilde, Cassan, Cédric, Fernando, Laurent, Wang, Feng, Hosseini, Mohsen, Chu-Van, Emeline, Le Cam, Laurent, Carroll, Martin, Selak, Mary A., Vey, Norbert, Castellano, Rémy, Fenaille, François, Turtoi, Andrei, Cazals, Guillaume, Bories, Pierre, Gibon, Yves, Nicolay, Brandon, Ronseaux, Sébastien, Marszalek, Joseph R., Takahashi, Koichi, DiNardo, Courtney D., Konopleva, Marina, Pancaldi, Véra, Collette, Yves, Bellvert, Floriant, Jourdan, Fabien, Linares, Laetitia K., Récher, Christian, Portais, Jean-Charles, Sarry, Jean-Emmanuel
Publicado no J Exp Med (2021)