GPCRs and cancer

Por Lappano, Rosamaria, Maggiolini, Marcello
Publicado em 2012

GPER Function in Breast Cancer: An Overview

Por Lappano, Rosamaria, Pisano, Assunta, Maggiolini, Marcello
Publicado em 2014

Response to “Comment on ‘Effects of Atrazine on Estrogen Receptor α– and G Protein–Coupled Receptor 30–Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fi...

Por Lappano, Rosamaria, Pupo, Marco, Maggiolini, Marcello
Publicado no Environ Health Perspect (2016)

Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF

Por Pandey, Deo Prakash, Lappano, Rosamaria, Albanito, Lidia, Madeo, Antonio, Maggiolini, Marcello, Picard, Didier
Publicado em 2009

HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)

Por De Francesco, Ernestina Marianna, Lappano, Rosamaria, Santolla, Maria Francesca, Marsico, Stefania, Caruso, Arnaldo, Maggiolini, Marcello
Publicado em 2013

MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells

Por Lappano, Rosamaria, Santolla, Maria Francesca, Pupo, Marco, Sinicropi, Maria Stefania, Caruso, Anna, Rosano, Camillo, Maggiolini, Marcello
Publicado em 2012

Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands

Por Rosano, Camillo, Ponassi, Marco, Santolla, Maria Francesca, Pisano, Assunta, Felli, Lamberto, Vivacqua, Adele, Maggiolini, Marcello, Lappano, Rosamaria
Publicado no AAPS J (2015)

The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes

Por Lappano, Rosamaria, Recchia, Anna Grazia, De Francesco, Ernestina Marianna, Angelone, Tommaso, Cerra, Maria Carmela, Picard, Didier, Maggiolini, Marcello
Publicado em 2011

Bisphenol A Induces Gene Expression Changes and Proliferative Effects through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts

Por Pupo, Marco, Pisano, Assunta, Lappano, Rosamaria, Santolla, Maria Francesca, De Francesco, Ernestina Marianna, Abonante, Sergio, Rosano, Camillo, Maggiolini, Marcello
Publicado em 2012

Recent Advances on the Role of G Protein-Coupled Receptors in Hypoxia-Mediated Signaling

Por Lappano, Rosamaria, Rigiracciolo, Damiano, De Marco, Paola, Avino, Silvia, Cappello, Anna Rita, Rosano, Camillo, Maggiolini, Marcello, De Francesco, Ernestina Marianna
Publicado no AAPS J (2016)

G-Protein–Coupled Receptor 30 and Estrogen Receptor-α Are Involved in the Proliferative Effects Induced by Atrazine in Ovarian Cancer Cells

Por Albanito, Lidia, Lappano, Rosamaria, Madeo, Antonio, Chimento, Adele, Prossnitz, Eric R., Cappello, Anna Rita, Dolce, Vincenza, Abonante, Sergio, Pezzi, Vincenzo, Maggiolini, Marcello
Publicado em 2008

Effects of Atrazine on Estrogen Receptor α– and G Protein–Coupled Receptor 30–Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts

Por Albanito, Lidia, Lappano, Rosamaria, Madeo, Antonio, Chimento, Adele, Prossnitz, Eric R., Cappello, Anna Rita, Dolce, Vincenza, Abonante, Sergio, Pezzi, Vincenzo, Maggiolini, Marcello
Publicado no Environ Health Perspect (2015)

GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response

Por De Marco, Paola, Lappano, Rosamaria, Francesco, Ernestina Marianna De, Cirillo, Francesca, Pupo, Marco, Avino, Silvia, Vivacqua, Adele, Abonante, Sergio, Picard, Didier, Maggiolini, Marcello
Publicado no Sci Rep (2016)

Epidermal Growth Factor Induces G Protein-Coupled Receptor 30 Expression in Estrogen Receptor-Negative Breast Cancer Cells

Por Albanito, Lidia, Sisci, Diego, Aquila, Saveria, Brunelli, Elvira, Vivacqua, Adele, Madeo, Antonio, Lappano, Rosamaria, Pandey, Deo Prakash, Picard, Didier, Mauro, Loredana, Andò, Sebastiano, Maggiolini, Marcello
Publicado em 2008

G Protein-coupled Estrogen Receptor Mediates the Up-regulation of Fatty Acid Synthase Induced by 17β-Estradiol in Cancer Cells and Cancer-associated Fibroblasts

Por Santolla, Maria Francesca, Lappano, Rosamaria, De Marco, Paola, Pupo, Marco, Vivacqua, Adele, Sisci, Diego, Abonante, Sergio, Iacopetta, Domenico, Cappello, Anna Rita, Dolce, Vincenza, Maggiolini, Marcello
Publicado em 2012

GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells

Por Rigiracciolo, Damiano Cosimo, Scarpelli, Andrea, Lappano, Rosamaria, Pisano, Assunta, Santolla, Maria Francesca, Avino, Silvia, De Marco, Paola, Bussolati, Benedetta, Maggiolini, Marcello, De Francesco, Ernestina Marianna
Publicado no Oncotarget (2015)

Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells

Por Avino, Silvia, Marco, Paola De, Cirillo, Francesca, Santolla, Maria Francesca, Francesco, Ernestina Marianna De, Perri, Maria Grazia, Rigiracciolo, Damiano, Dolce, Vincenza, Belfiore, Antonino, Maggiolini, Marcello, Lappano, Rosamaria, Vivacqua, Adele
Publicado no Oncotarget (2016)

Copper activates HIF-1α/GPER/VEGF signalling in cancer cells

Por Rigiracciolo, Damiano Cosimo, Scarpelli, Andrea, Lappano, Rosamaria, Pisano, Assunta, Santolla, Maria Francesca, De Marco, Paola, Cirillo, Francesca, Cappello, Anna Rita, Dolce, Vincenza, Belfiore, Antonino, Maggiolini, Marcello, De Francesco, Ernestina Marianna
Publicado no Oncotarget (2015)

A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models

Por Lappano, Rosamaria, Rosano, Camillo, Pisano, Assunta, Santolla, Maria Francesca, De Francesco, Ernestina Marianna, De Marco, Paola, Dolce, Vincenza, Ponassi, Marco, Felli, Lamberto, Cafeo, Grazia, Kohnke, Franz Heinrich, Abonante, Sergio, Maggiolini, Marcello
Publicado no Dis Model Mech (2015)