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G-Protein–Coupled Receptor 30 and Estrogen Receptor-α Are Involved in the Proliferative Effects Induced by Atrazine in Ovarian Cancer Cells

BACKGROUND: Atrazine, one of the most common pesticide contaminants, has been shown to up-regulate aromatase activity in certain estrogen-sensitive tumors without binding or activating the estrogen receptor (ER). Recent investigations have demonstrated that the orphan G-protein–coupled receptor 30 (...

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Main Authors: Albanito, Lidia, Lappano, Rosamaria, Madeo, Antonio, Chimento, Adele, Prossnitz, Eric R., Cappello, Anna Rita, Dolce, Vincenza, Abonante, Sergio, Pezzi, Vincenzo, Maggiolini, Marcello
Formato: Artigo
Idioma:Inglês
Publicado: National Institute of Environmental Health Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599758/
https://ncbi.nlm.nih.gov/pubmed/19079715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.11297
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