A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models

Estrogens regulate numerous pathophysiological processes, mainly by binding to and activating estrogen receptor (ER)α and ERβ. Increasing amounts of evidence have recently demonstrated that G-protein coupled receptor 30 (GPR30; also known as GPER) is also involved in diverse biological responses to...

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Dettagli Bibliografici
Pubblicato in:Dis Model Mech
Autori principali: Lappano, Rosamaria, Rosano, Camillo, Pisano, Assunta, Santolla, Maria Francesca, De Francesco, Ernestina Marianna, De Marco, Paola, Dolce, Vincenza, Ponassi, Marco, Felli, Lamberto, Cafeo, Grazia, Kohnke, Franz Heinrich, Abonante, Sergio, Maggiolini, Marcello
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610237/
https://ncbi.nlm.nih.gov/pubmed/26183213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.021071
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