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MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells

INTRODUCTION: The multiple biological responses to estrogens are mainly mediated by the classical estrogen receptors ERα and ERβ, which act as ligand-activated transcription factors. ERα exerts a main role in the development of breast cancer; therefore, the ER antagonist tamoxifen has been widely us...

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Detalhes bibliográficos
Main Authors: Lappano, Rosamaria, Santolla, Maria Francesca, Pupo, Marco, Sinicropi, Maria Stefania, Caruso, Anna, Rosano, Camillo, Maggiolini, Marcello
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496129/
https://ncbi.nlm.nih.gov/pubmed/22251451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3096
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