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MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells
INTRODUCTION: The multiple biological responses to estrogens are mainly mediated by the classical estrogen receptors ERα and ERβ, which act as ligand-activated transcription factors. ERα exerts a main role in the development of breast cancer; therefore, the ER antagonist tamoxifen has been widely us...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496129/ https://ncbi.nlm.nih.gov/pubmed/22251451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3096 |
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