GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells

Aldosterone induces relevant effects binding to the mineralcorticoid receptor (MR), which acts as a ligand-gated transcription factor. Alternate mechanisms can mediate the action of aldosterone such as the activation of epidermal growth factor receptor (EGFR), MAPK/ERK, transcription factors and ion...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rigiracciolo, Damiano Cosimo, Scarpelli, Andrea, Lappano, Rosamaria, Pisano, Assunta, Santolla, Maria Francesca, Avino, Silvia, De Marco, Paola, Bussolati, Benedetta, Maggiolini, Marcello, De Francesco, Ernestina Marianna
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper: Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807985/
https://ncbi.nlm.nih.gov/pubmed/26646587
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