Simultaneous targeting of HER family pro-survival signaling with Pan-HER antibody mixture is highly effective in TNBC: a preclinical trial with PDXs

por Reddy, Tejaswini P., Choi, Dong S., Anselme, Ann C., Qian, Wei, Chen, Wen, Lantto, Johan, Horak, Ivan D., Kragh, Michael, Chang, Jenny C., Rosato, Roberto R.
Publicado en Breast Cancer Res (2020)

Capturing the Natural Diversity of the Human Antibody Response against Vaccinia Virus

por Lantto, Johan, Haahr Hansen, Margit, Rasmussen, Søren Kofoed, Steinaa, Lucilla, Poulsen, Tine R., Duggan, Jackie, Dennis, Mike, Naylor, Irene, Easterbrook, Linda, Bregenholt, Søren, Haurum, John, Jensen, Allan
Publicado 2011

In vivo imaging of therapy response to a novel Pan-HER antibody mixture using FDG and FLT positron emission tomography

por Nielsen, Carsten H., Jensen, Mette M., Kristensen, Lotte K., Dahlman, Anna, Fröhlich, Camilla, Jacobsen, Helle J., Poulsen, Thomas T., Lantto, Johan, Horak, Ivan D., Kragh, Michael, Kjaer, Andreas
Publicado en Oncotarget (2015)

CD4(+) and CD8a(+) PET imaging predicts response to novel PD-1 checkpoint inhibitor: studies of Sym021 in syngeneic mouse cancer models

por Kristensen, Lotte K., Fröhlich, Camilla, Christensen, Camilla, Melander, Maria C., Poulsen, Thomas T., Galler, Gunther R., Lantto, Johan, Horak, Ivan D., Kragh, Michael, Nielsen, Carsten H., Kjaer, Andreas
Publicado en Theranostics (2019)

Passive Immunotherapies Protect WRvFire and IHD-J-Luc Vaccinia Virus-Infected Mice from Lethality by Reducing Viral Loads in the Upper Respiratory Tract and Internal Organs

por Zaitseva, Marina, Kapnick, Senta M., Meseda, Clement A., Shotwell, Elisabeth, King, Lisa R., Manischewitz, Jody, Scott, John, Kodihalli, Shantha, Merchlinsky, Michael, Nielsen, Henriette, Lantto, Johan, Weir, Jerry P., Golding, Hana
Publicado 2011

Targeting the HER family with Pan-HER effectively overcomes resistance to cetuximab

por Iida, Mari, Bahrar, Harsh, Brand, Toni M, Pearson, Hannah E, Coan, John P, Orbuch, Rachel A, Flanigan, Bailey G, Swick, Adam D, Prabakaran, Prashanth, Lantto, Johan, Horak, Ivan D., Kragh, Michael, Salgia, Ravi, Kimple, Randy J, Wheeler, Deric L
Publicado en Mol Cancer Ther (2016)

Sym021, a promising anti-PD1 clinical candidate antibody derived from a new chicken antibody discovery platform

por Gjetting, Torben, Gad, Monika, Fröhlich, Camilla, Lindsted, Trine, Melander, Maria C, Bhatia, Vikram K, Grandal, Michael M, Dietrich, Nikolaj, Uhlenbrock, Franziska, Galler, Gunther R, Strandh, Magnus, Lantto, Johan, Bouquin, Thomas, Horak, Ivan D, Kragh, Michael, Pedersen, Mikkel W, Koefoed, Klaus
Publicado en MAbs (2019)

An ERBB1-3 Neutralizing Antibody Mixture With High Activity Against Drug-Resistant HER2+ Breast Cancers With ERBB Ligand Overexpression

por Schwarz, Luis J, Hutchinson, Katherine E, Rexer, Brent N, Estrada, Mónica Valeria, Gonzalez Ericsson, Paula I, Sanders, Melinda E, Dugger, Teresa C, Formisano, Luigi, Guerrero-Zotano, Angel, Red-Brewer, Monica, Young, Christian D, Lantto, Johan, Pedersen, Mikkel W, Kragh, Michael, Horak, Ivan D, Arteaga, Carlos L
Publicado en J Natl Cancer Inst (2017)

The Genomic Landscape of Response to EGFR Blockade in Colorectal Cancer

por Bertotti, Andrea, Papp, Eniko, Jones, Siân, Adleff, Vilmos, Anagnostou, Valsamo, Lupo, Barbara, Sausen, Mark, Phallen, Jillian, Hruban, Carolyn A., Tokheim, Collin, Niknafs, Noushin, Nesselbush, Monica, Lytle, Karli, Sassi, Francesco, Cottino, Francesca, Migliardi, Giorgia, Zanella, Eugenia R., Ribero, Dario, Russolillo, Nadia, Mellano, Alfredo, Muratore, Andrea, Paraluppi, Gianluca, Salizzoni, Mauro, Marsoni, Silvia, Kragh, Michael, Lantto, Johan, Cassingena, Andrea, Li, Qing Kay, Karchin, Rachel, Scharpf, Robert, Sartore-Bianchi, Andrea, Siena, Salvatore, Diaz, Luis A., Trusolino, Livio, Velculescu, Victor E.
Publicado en Nature (2015)