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Targeting the HER family with Pan-HER effectively overcomes resistance to cetuximab

Cetuximab, an antibody against the Epidermal Growth Factor Receptor (EGFR) has shown efficacy in treating head and neck squamous cell carcinoma (HNSCC), metastatic colorectal cancer and non-small cell lung cancer (NSCLC). Despite the clinical success of cetuximab, many patients do not respond to cet...

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Podrobná bibliografie
Vydáno v:Mol Cancer Ther
Hlavní autoři: Iida, Mari, Bahrar, Harsh, Brand, Toni M, Pearson, Hannah E, Coan, John P, Orbuch, Rachel A, Flanigan, Bailey G, Swick, Adam D, Prabakaran, Prashanth, Lantto, Johan, Horak, Ivan D., Kragh, Michael, Salgia, Ravi, Kimple, Randy J, Wheeler, Deric L
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010956/
https://ncbi.nlm.nih.gov/pubmed/27422810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0012
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