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Sym021, a promising anti-PD1 clinical candidate antibody derived from a new chicken antibody discovery platform
Discovery of therapeutic antibodies is a field of intense development, where immunization of rodents remains a major source of antibody candidates. However, high orthologue protein sequence homology between human and rodent species disfavors generation of antibodies against functionally conserved bi...
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| 出版年: | MAbs |
|---|---|
| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6601539/ https://ncbi.nlm.nih.gov/pubmed/31046547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1596514 |
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