Sym021, a promising anti-PD1 clinical candidate antibody derived from a new chicken antibody discovery platform

Discovery of therapeutic antibodies is a field of intense development, where immunization of rodents remains a major source of antibody candidates. However, high orthologue protein sequence homology between human and rodent species disfavors generation of antibodies against functionally conserved bi...

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Bibliografiske detaljer
Udgivet i:MAbs
Main Authors: Gjetting, Torben, Gad, Monika, Fröhlich, Camilla, Lindsted, Trine, Melander, Maria C, Bhatia, Vikram K, Grandal, Michael M, Dietrich, Nikolaj, Uhlenbrock, Franziska, Galler, Gunther R, Strandh, Magnus, Lantto, Johan, Bouquin, Thomas, Horak, Ivan D, Kragh, Michael, Pedersen, Mikkel W, Koefoed, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601539/
https://ncbi.nlm.nih.gov/pubmed/31046547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1596514
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