Sym004, a novel anti-EGFR antibody mixture augments radiation response in human lung and head and neck cancers

Sym004 represents a novel EGFR targeting approach comprised of a mixture of two anti-EGFR antibodies directed against distinct epitopes of EGFR. In contrast to single anti-EGFR antibodies, Sym004 induces rapid and highly efficient degradation of EGFR. In the current study, we examine the capacity of...

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Bibliographic Details
Main Authors: Huang, Shyhmin, Peet, Chimera R., Saker, Jarob, Li, Chunrong, Armstrong, Eric A., Kragh, Michael, Pedersen, Mikkel W., Harari, Paul M.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960925/
https://ncbi.nlm.nih.gov/pubmed/24130052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0587
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