Sym021, a promising anti-PD1 clinical candidate antibody derived from a new chicken antibody discovery platform

Discovery of therapeutic antibodies is a field of intense development, where immunization of rodents remains a major source of antibody candidates. However, high orthologue protein sequence homology between human and rodent species disfavors generation of antibodies against functionally conserved bi...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Gjetting, Torben, Gad, Monika, Fröhlich, Camilla, Lindsted, Trine, Melander, Maria C, Bhatia, Vikram K, Grandal, Michael M, Dietrich, Nikolaj, Uhlenbrock, Franziska, Galler, Gunther R, Strandh, Magnus, Lantto, Johan, Bouquin, Thomas, Horak, Ivan D, Kragh, Michael, Pedersen, Mikkel W, Koefoed, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601539/
https://ncbi.nlm.nih.gov/pubmed/31046547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1596514
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