The junctophilin family of proteins: From bench to bedside

Por Landstrom, Andrew P., Beavers, David L., Wehrens, Xander H.T.
Publicado em 2014

Junctophilin-2 at the intersection of arrhythmia and pathologic cardiac remodeling

Por Quick, Ann P., Landstrom, Andrew P., Wehrens, Xander H.T.
Publicado no Heart Rhythm (2015)

It’s not the heart: autonomic nervous system predisposition to lethal ventricular arrhythmias

Por Landstrom, Andrew P., Sun, Jenny J., Ray, Russell S., Wehrens, Xander H.T.
Publicado no Heart Rhythm (2015)

Emerging roles of junctophilin-2 in the heart and implications for cardiac diseases

Por Beavers, David L., Landstrom, Andrew P., Chiang, David Y., Wehrens, Xander H.T.
Publicado no Cardiovasc Res (2014)

Molecular evolution of the junctophilin gene family

Por Garbino, Alejandro, van Oort, Ralph J., Dixit, Sayali S., Landstrom, Andrew P., Ackerman, Michael J., Wehrens, Xander H. T.
Publicado em 2009

A Mutation in TNNC1-encoded Cardiac Troponin C, TNNC1-A31S, Predisposes to Hypertrophic Cardiomyopathy and Ventricular Fibrillation

Por Parvatiyar, Michelle S., Landstrom, Andrew P., Figueiredo-Freitas, Cicero, Potter, James D., Ackerman, Michael J., Pinto, Jose Renato
Publicado em 2012

Distinguishing Hypertrophic Cardiomyopathy-Associated Mutations from Background Genetic Noise

Por Kapplinger, Jamie D., Landstrom, Andrew P., Bos, J. Martijn, Salisbury, Benjamin A., Callis, Thomas E., Ackerman, Michael J.
Publicado no J Cardiovasc Transl Res (2014)

Reduced junctional Na(+)/Ca(2+)-exchanger activity contributes to sarcoplasmic reticulum Ca(2+) leak in junctophilin-2-deficient mice

Por Wang, Wei, Landstrom, Andrew P., Wang, Qiongling, Munro, Michelle L., Beavers, David, Ackerman, Michael J., Soeller, Christian, Wehrens, Xander H. T.
Publicado em 2014

Junctophilin-2 Expression Silencing Causes Cardiocyte Hypertrophy and Abnormal Intracellular Calcium-Handling

Por Landstrom, Andrew P., Kellen, Cherisse A., Dixit, Sayali S., van Oort, Ralph J., Garbino, Alejandro, Weisleder, Noah, Ma, Jianjie, Wehrens, Xander H.T., Ackerman, Michael J.
Publicado em 2011

Molecular and Functional Characterization of Novel Hypertrophic Cardiomyopathy Susceptibility Mutations in TNNC1- Encoded Troponin C

Por Landstrom, Andrew P., Parvatiyar, Michelle S., Pinto, Jose R., Marquardt, Michelle L., Bos, J. Martijn, Tester, David J., Ommen, Steve R., Potter, James D., Ackerman, Michael J.
Publicado em 2008

Junctophilin-2 is necessary for T-tubule maturation during mouse heart development

Por Reynolds, Julia O., Chiang, David Y., Wang, Wei, Beavers, David L., Dixit, Sayali S., Skapura, Darlene G., Landstrom, Andrew P., Song, Long-Sheng, Ackerman, Michael J., Wehrens, Xander H.T.
Publicado em 2013

Hypertrophic Cardiomyopathy Cardiac Troponin C Mutations Differentially Affect Slow Skeletal and Cardiac Muscle Regulation

Por Veltri, Tiago, Landim-Vieira, Maicon, Parvatiyar, Michelle S., Gonzalez-Martinez, David, Dieseldorff Jones, Karissa M., Michell, Clara A., Dweck, David, Landstrom, Andrew P., Chase, P. Bryant, Pinto, Jose R.
Publicado no Front Physiol (2017)

Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization

Por Beavers, David L., Wang, Wei, Ather, Sameer, Voigt, Niels, Garbino, Alejandro, Dixit, Sayali S., Landstrom, Andrew P., Li, Na, Wang, Qiongling, Olivotto, Iacopo, Dobrev, Dobromir, Ackerman, Michael J., Wehrens, Xander H.T.
Publicado em 2013

Disrupted Junctional Membrane Complexes and Hyperactive Ryanodine Receptors Following Acute Junctophilin Knockdown in Mice

Por van Oort, Ralph J., Garbino, Alejandro, Wang, Wei, Dixit, Sayali S., Landstrom, Andrew P., Gaur, Namit, De Almeida, Angela C., Skapura, Darlene G., Rudy, Yoram, Burns, Alan R., Ackerman, Michael J., Wehrens, Xander H.T.
Publicado em 2011

Interpreting Incidentally Identified Variants in Genes Associated with Catecholaminergic Polymorphic Ventricular Tachycardia in a Large Cohort of Clinical Whole Exome Genetic Test...

Por Landstrom, Andrew P., Dailey-Schwartz, Andrew L., Rosenfeld, Jill A., Yang, Yaping, McLean, Margaret J., Miyake, Christina Y., Valdes, Santiago O., Fan, Yuxin, Allen, Hugh D., Penny, Daniel J., Kim, Jeffrey J.
Publicado no Circ Arrhythm Electrophysiol (2017)

Mutations in JPH2-Encoded Junctophilin-2 Associated with Hypertrophic Cardiomyopathy in Humans

Por Landstrom, Andrew P., Weisleder, Noah, Batalden, Karin B., Bos, J. Martijn, Tester, David J., Ommen, Steve R., Wehrens, Xander H.T, Claycomb, William C., Ko, Jae-Kyun, Hwang, Moonsun, Pan, Zui, Ma, Jianjie, Ackerman, Michael J.
Publicado no J Mol Cell Cardiol (2007)

Novel Junctophilin-2 Mutation A405S Is Associated With Basal Septal Hypertrophy and Diastolic Dysfunction

Por Quick, Ann P., Landstrom, Andrew P., Wang, Qiongling, Beavers, David L., Reynolds, Julia O., Barreto-Torres, Giselle, Tran, Viet, Showell, Jordan, Philippen, Leonne E., Morris, Shaine A., Skapura, Darlene, Bos, J. Martijn, Pedersen, Steen E., Pautler, Robia G., Ackerman, Michael J., Wehrens, Xander H.T.
Publicado no JACC Basic Transl Sci (2017)