Antisense MicroRNA Therapeutics in Cardiovascular Disease: Quo Vadis?

por Philippen, Leonne E, Dirkx, Ellen, Wit, Jan B M, Burggraaf, Koos, de Windt, Leon J, da Costa Martins, Paula A
Publicado en Mol Ther (2015)

Atrial-Specific Gene Delivery Using an Adeno-Associated Viral Vector

por Ni, Li, Scott, Larry, Campbell, Hannah M., Pan, Xiaolu, Alsina, Katherina M., Reynolds, Julia, Philippen, Leonne E., Hulsurkar, Mohit, Lagor, William R., Li, Na, Wehrens, Xander H.T.
Publicado en Circ Res (2019)

Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca(2+) release

por Reynolds, Julia O., Quick, Ann P., Wang, Qiongling, Beavers, David L., Philippen, Leonne E., Showell, Jordan, Barreto-Torres, Giselle, Theurauf, Donna J., Doroudgar, Shirin, Glembotski, Christopher C., Wehrens, Xander H.T.
Publicado en Int J Cardiol (2016)

‘Striated Muscle Preferentially Expressed Protein Kinase’ (SPEG) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity

por Quick, Ann P., Wang, Qiongling, Philippen, Leonne E., Barreto-Torres, Giselle, Chiang, David Y., Beavers, David, Wang, Guoliang, Khalid, Maha, Reynolds, Julia O., Campbell, Hannah M., Showell, Jordan, McCauley, Mark D., Scholten, Arjen, Wehrens, Xander H. T.
Publicado en Circ Res (2016)

Novel Junctophilin-2 Mutation A405S Is Associated With Basal Septal Hypertrophy and Diastolic Dysfunction

por Quick, Ann P., Landstrom, Andrew P., Wang, Qiongling, Beavers, David L., Reynolds, Julia O., Barreto-Torres, Giselle, Tran, Viet, Showell, Jordan, Philippen, Leonne E., Morris, Shaine A., Skapura, Darlene, Bos, J. Martijn, Pedersen, Steen E., Pautler, Robia G., Ackerman, Michael J., Wehrens, Xander H.T.
Publicado en JACC Basic Transl Sci (2017)

Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure

por Raso, Andrea, Dirkx, Ellen, Philippen, Leonne E., Fernandez-Celis, Amaya, De Majo, Federica, Sampaio-Pinto, Vasco, Sansonetti, Marida, Juni, Rio, el Azzouzi, Hamid, Calore, Martina, Bitsch, Nicole, Olieslagers, Servé, Oerlemans, Martinus I.F.J., Huibers, Manon M., de Weger, Roel A., Reckman, Yolan J., Pinto, Yigal M., Zentilin, Lorena, Zacchigna, Serena, Giacca, Mauro, da Costa Martins, Paula A., López-Andrés, Natalia, De Windt, Leon J.
Publicado en Mol Ther (2019)