‘Striated Muscle Preferentially Expressed Protein Kinase’ (SPEG) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity

RATIONALE: Junctional membrane complexes (JMC) in myocytes are critical microdomains, in which excitation-contraction coupling occurs. Structural and functional disruption of JMCs underlies contractile dysfunction in failing hearts. However, the role of newly identified JMC protein ‘striated muscle...

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Bibliographic Details
Published in:Circ Res
Main Authors: Quick, Ann P., Wang, Qiongling, Philippen, Leonne E., Barreto-Torres, Giselle, Chiang, David Y., Beavers, David, Wang, Guoliang, Khalid, Maha, Reynolds, Julia O., Campbell, Hannah M., Showell, Jordan, McCauley, Mark D., Scholten, Arjen, Wehrens, Xander H. T.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218854/
https://ncbi.nlm.nih.gov/pubmed/27729468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.309977
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