Oxidized CaMKII is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) patients are prone to ventricular arrhythmias, which may be caused by abnormal calcium (Ca(2+)) homeostasis and elevated reactive oxygen species (ROS). Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is vital for normal Ca(2+) homeostasis, but exc...

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Detalhes bibliográficos
Publicado no:Circ Arrhythm Electrophysiol
Main Authors: Wang, Qiongling, Quick, Ann P., Cao, Shuyi, Reynolds, Julia, Chiang, David Y., Beavers, David, Li, Na, Wang, Guoliang, Rodney, George G., Anderson, Mark E., Wehrens, Xander HT.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903581/
https://ncbi.nlm.nih.gov/pubmed/29654126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.117.005682
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