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Crosstalk between RyR2 Oxidation and Phosphorylation Contributes to Cardiac dysfunction in Mice with Duchenne Muscular Dystrophy
BACKGROUND: Patients with Duchenne muscular dystrophy (DMD) are at risk of developing cardiomyopathy and cardiac arrhythmias. Studies in a mouse model of DMD revealed that enhanced sarcoplasmic reticulum (SR) Ca(2+) leak contributes to the pathogenesis of cardiac dysfunction. In view of recent data...
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| Publicado no: | J Mol Cell Cardiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689641/ https://ncbi.nlm.nih.gov/pubmed/26555638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.11.009 |
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