Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

Patients with Duchenne muscular dystrophy (DMD) have a progressive dilated cardiomyopathy associated with fatal cardiac arrhythmias. Electrical and functional abnormalities have been attributed to cardiac fibrosis; however, electrical abnormalities may occur in the absence of overt cardiac histopath...

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Main Authors: Fauconnier, Jérémy, Thireau, Jérôme, Reiken, Steven, Cassan, Cécile, Richard, Sylvain, Matecki, Stefan, Marks, Andrew R., Lacampagne, Alain
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824377/
https://ncbi.nlm.nih.gov/pubmed/20080623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908540107
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