Short-Coupled Polymorphic Ventricular Tachycardia At Rest Linked to a Novel Ryanodine Receptor (RyR2) Mutation: Leaky RyR2 Channels Under Non-Stress Conditions

BACKGROUND: Ryanodine receptor (RyR2) mutations have largely been associated with catecholaminergic polymorphic ventricular tachycardia (PMVT). The role of RyR2 mutations in the pathogenesis of arrhythmias and syncope at rest is unknown. We sought to characterize the clinical and functional characte...

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Veröffentlicht in:Int J Cardiol
Hauptverfasser: Cheung, Jim W., Meli, Albano C., Xie, Wenjun, Mittal, Suneet, Reiken, Steven, Wronska, Anetta, Xu, Linna, Steinberg, Jonathan S., Markowitz, Steven M., Iwai, Sei, Lacampagne, Alain, Lerman, Bruce B., Marks, Andrew R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281514/
https://ncbi.nlm.nih.gov/pubmed/25463374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2014.11.119
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