From delocalized lipophilic cations to hypoxia: Blocking tumor cell mitochondrial function leads to therapeutic gain with glycolytic inhibitors

di Kurtoglu, Metin, Lampidis, Theodore J.
Pubblicazione 2009

Intrinsically lower AKT, mTOR and HIF activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines

di Wangpaichitr, Medhi, Savaraj, Niramol, Maher, Johnathan, Kurtoglu, Metin, Lampidis, Theodore J.
Pubblicazione 2008

High endoplasmic reticulum activity renders multiple myeloma cells hypersensitive to mitochondrial inhibitors

di Kurtoglu, Metin, Philips, Katherine, Liu, Huaping, Boise, Lawrence H., Lampidis, Theodore J.
Pubblicazione 2009

Activation of the Unfolded Protein Response by 2-Deoxy-d-Glucose Inhibits Kaposi's Sarcoma-Associated Herpesvirus Replication and Gene Expression

di Leung, Howard J., Duran, Elda M., Kurtoglu, Metin, Andreansky, Samita, Lampidis, Theodore J., Mesri, Enrique A.
Pubblicazione 2012

2-Deoxy-D-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion

di Xi, Haibin, Kurtoglu, Metin, Liu, Huaping, Wangpaichitr, Medhi, You, Min, Liu, Xiongfei, Savaraj, Niramol, Lampidis, Theodore J.
Pubblicazione 2010

Focal, Periocular Delivery of 2-Deoxy-d-Glucose as Adjuvant to Chemotherapy for Treatment of Advanced Retinoblastoma

di Piña, Yolanda, Houston, Samuel K., Murray, Timothy G., Boutrid, Hinda, Celdran, Magda, Feuer, William, Shi, Wei, Hernandez, Eleut, Lampidis, Theodore J.
Pubblicazione 2010

Increased sensitivity to glucose starvation correlates with downregulation of glycogen phosphorylase isoform PYGB in tumor cell lines resistant to 2-deoxy-d-glucose

di Philips, Katherine B., Kurtoglu, Metin, Leung, Howard J., Liu, Huaping, Gao, Ningguo, Lehrman, Mark A., Murray, Timothy G., Lampidis, Theodore J.
Pubblicato in Cancer Chemother Pharmacol (2013)

2-DEOXY-GLUCOSE DOWN REGULATES ENDOTHELIAL AKT AND ERK VIA INTERFERENCE WITH N-LINKED GLYCOSYLATION, INDUCTION OF ENDOPLASMIC RETICULUM STRESS AND GSK-3β ACTIVATION

di Kovács, Krisztina, Decatur, Christina, Toro, Marcela, Pham, Dien G., Liu, Huaping, Jing, Yuqi, Murray, Timothy G., Lampidis, Theodore J., Merchan, Jaime R.
Pubblicato in Mol Cancer Ther (2015)

Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress

di Leclerc, Guy J., DeSalvo, Joanna, Du, Jianfeng, Gao, Ningguo, Leclerc, Gilles M., Lehrman, Mark A., Lampidis, Theodore J., Barredo, Julio C
Pubblicato in Leuk Res (2015)

Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress

di Liu, Huaping, Kurtoglu, Metin, León-Annicchiarico, Clara Lucia, Munoz-Pinedo, Cristina, Barredo, Julio, Leclerc, Guy, Merchan, Jaime, Liu, Xiongfei, Lampidis, Theodore J.
Pubblicato in Oncotarget (2016)

Targeting the kynurenine pathway for the treatment of cisplatin resistant lung cancer

di Nguyen, Dan JM., Theodoropoulos, George, Li, Ying-Ying, Wu, Chunjing, sha, Wei, Feun, Lynn G., Lampidis, Theodore J., Savaraj, Niramol, Wangpaichitr, Medhi
Pubblicato in Mol Cancer Res (2019)

Retinoblastoma treatment: impact of the glycolytic inhibitor 2-deoxy-d-glucose on molecular genomics expression in LH(BETA)T(AG) retinal tumors

di Piña, Yolanda, Houston, Samuel K, Murray, Timothy G, Koru-Sengul, Tulay, Decatur, Christina, Scott, William K, Nathanson, Lubov, Clarke, Jennifer, Lampidis, Theodore J
Pubblicazione 2012

Antiangiogenic Activity of 2-Deoxy-D-Glucose

di Merchan, Jaime R., Kovács, Krisztina, Railsback, Jaclyn W., Kurtoglu, Metin, Jing, Yuqi, Piña, Yolanda, Gao, Ningguo, Murray, Timothy G., Lehrman, Mark A., Lampidis, Theodore J.
Pubblicazione 2010

Regulation of Mitochondrial Respiratory Chain Complex Levels, Organization, and Function by Arginyltransferase 1

di Jiang, Chunhua, Moorthy, Balaji T., Patel, Devang M., Kumar, Akhilesh, Morgan, William M., Alfonso, Belkis, Huang, Jingyu, Lampidis, Theodore J., Isom, Daniel G., Barrientos, Antoni, Fontanesi, Flavia, Zhang, Fangliang
Pubblicato in Front Cell Dev Biol (2020)