Structure-based molecular modeling in SAR analysis and lead optimization

gan Temml, Veronika, Kutil, Zsofia
Cyhoeddwyd yn Comput Struct Biotechnol J (2021)

Prospective performance evaluation of selected common virtual screening tools. Case study: Cyclooxygenase (COX) 1 and 2

gan Kaserer, Teresa, Temml, Veronika, Kutil, Zsofia, Vanek, Tomas, Landa, Premysl, Schuster, Daniela
Cyhoeddwyd yn Eur J Med Chem (2015)

Impact of Wines and Wine Constituents on Cyclooxygenase-1, Cyclooxygenase-2, and 5-Lipoxygenase Catalytic Activity

gan Kutil, Zsofia, Temml, Veronika, Maghradze, David, Pribylova, Marie, Dvorakova, Marcela, Schuster, Daniela, Vanek, Tomas, Landa, Premysl
Cyhoeddwyd 2014

Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models

gan Tavares, Maurício T., Shen, Sida, Knox, Tessa, Hadley, Melissa, Kutil, Zsófia, Bařinka, Cyril, Villagra, Alejandro, Kozikowski, Alan P.
Cyhoeddwyd yn ACS Med Chem Lett (2017)

Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors

gan Kutil, Zsófia, Mikešová, Jana, Zessin, Matthes, Meleshin, Marat, Nováková, Zora, Alquicer, Glenda, Kozikowski, Alan, Sippl, Wolfgang, Bařinka, Cyril, Schutkowski, Mike
Cyhoeddwyd yn ACS Omega (2019)

Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening

gan Temml, Veronika, Garscha, Ulrike, Romp, Erik, Schubert, Gregor, Gerstmeier, Jana, Kutil, Zsofia, Matuszczak, Barbara, Waltenberger, Birgit, Stuppner, Hermann, Werz, Oliver, Schuster, Daniela
Cyhoeddwyd yn Sci Rep (2017)

The disordered N-terminus of HDAC6 is a microtubule-binding domain critical for efficient tubulin deacetylation

gan Ustinova, Kseniya, Novakova, Zora, Saito, Makoto, Meleshin, Marat, Mikesova, Jana, Kutil, Zsofia, Baranova, Petra, Havlinova, Barbora, Schutkowski, Mike, Matthias, Patrick, Barinka, Cyril
Cyhoeddwyd yn J Biol Chem (2020)

Human histone deacetylase 6 shows strong preference for tubulin dimers over assembled microtubules

gan Skultetyova, Lubica, Ustinova, Kseniya, Kutil, Zsofia, Novakova, Zora, Pavlicek, Jiri, Mikesova, Jana, Trapl, Dalibor, Baranova, Petra, Havlinova, Barbora, Hubalek, Martin, Lansky, Zdenek, Barinka, Cyril
Cyhoeddwyd yn Sci Rep (2017)

Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome

gan Kozikowski, Alan P., Shen, Sida, Pardo, Marta, Tavares, Maurício T., Szarics, Dora, Benoy, Veronick, Zimprich, Chad A., Kutil, Zsófia, Zhang, Guiping, Bařinka, Cyril, Robers, Matthew B., Van Den Bosch, Ludo, Eubanks, James H., Jope, Richard S.
Cyhoeddwyd yn ACS Chem Neurosci (2018)