Structure-based molecular modeling in SAR analysis and lead optimization

Yazar: Temml, Veronika, Kutil, Zsofia
Yayımlandı Comput Struct Biotechnol J (2021)

Prospective performance evaluation of selected common virtual screening tools. Case study: Cyclooxygenase (COX) 1 and 2

Yazar: Kaserer, Teresa, Temml, Veronika, Kutil, Zsofia, Vanek, Tomas, Landa, Premysl, Schuster, Daniela
Yayımlandı Eur J Med Chem (2015)

Impact of Wines and Wine Constituents on Cyclooxygenase-1, Cyclooxygenase-2, and 5-Lipoxygenase Catalytic Activity

Yazar: Kutil, Zsofia, Temml, Veronika, Maghradze, David, Pribylova, Marie, Dvorakova, Marcela, Schuster, Daniela, Vanek, Tomas, Landa, Premysl
Baskı/Yayın Bilgisi 2014

Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models

Yazar: Tavares, Maurício T., Shen, Sida, Knox, Tessa, Hadley, Melissa, Kutil, Zsófia, Bařinka, Cyril, Villagra, Alejandro, Kozikowski, Alan P.
Yayımlandı ACS Med Chem Lett (2017)

Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors

Yazar: Kutil, Zsófia, Mikešová, Jana, Zessin, Matthes, Meleshin, Marat, Nováková, Zora, Alquicer, Glenda, Kozikowski, Alan, Sippl, Wolfgang, Bařinka, Cyril, Schutkowski, Mike
Yayımlandı ACS Omega (2019)

Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening

Yazar: Temml, Veronika, Garscha, Ulrike, Romp, Erik, Schubert, Gregor, Gerstmeier, Jana, Kutil, Zsofia, Matuszczak, Barbara, Waltenberger, Birgit, Stuppner, Hermann, Werz, Oliver, Schuster, Daniela
Yayımlandı Sci Rep (2017)

The disordered N-terminus of HDAC6 is a microtubule-binding domain critical for efficient tubulin deacetylation

Yazar: Ustinova, Kseniya, Novakova, Zora, Saito, Makoto, Meleshin, Marat, Mikesova, Jana, Kutil, Zsofia, Baranova, Petra, Havlinova, Barbora, Schutkowski, Mike, Matthias, Patrick, Barinka, Cyril
Yayımlandı J Biol Chem (2020)

Human histone deacetylase 6 shows strong preference for tubulin dimers over assembled microtubules

Yazar: Skultetyova, Lubica, Ustinova, Kseniya, Kutil, Zsofia, Novakova, Zora, Pavlicek, Jiri, Mikesova, Jana, Trapl, Dalibor, Baranova, Petra, Havlinova, Barbora, Hubalek, Martin, Lansky, Zdenek, Barinka, Cyril
Yayımlandı Sci Rep (2017)

Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome

Yazar: Kozikowski, Alan P., Shen, Sida, Pardo, Marta, Tavares, Maurício T., Szarics, Dora, Benoy, Veronick, Zimprich, Chad A., Kutil, Zsófia, Zhang, Guiping, Bařinka, Cyril, Robers, Matthew B., Van Den Bosch, Ludo, Eubanks, James H., Jope, Richard S.
Yayımlandı ACS Chem Neurosci (2018)