Structure-based molecular modeling in SAR analysis and lead optimization

av Temml, Veronika, Kutil, Zsofia
I publikationen Comput Struct Biotechnol J (2021)

Prospective performance evaluation of selected common virtual screening tools. Case study: Cyclooxygenase (COX) 1 and 2

av Kaserer, Teresa, Temml, Veronika, Kutil, Zsofia, Vanek, Tomas, Landa, Premysl, Schuster, Daniela
I publikationen Eur J Med Chem (2015)

Impact of Wines and Wine Constituents on Cyclooxygenase-1, Cyclooxygenase-2, and 5-Lipoxygenase Catalytic Activity

av Kutil, Zsofia, Temml, Veronika, Maghradze, David, Pribylova, Marie, Dvorakova, Marcela, Schuster, Daniela, Vanek, Tomas, Landa, Premysl
Publicerad 2014

Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models

av Tavares, Maurício T., Shen, Sida, Knox, Tessa, Hadley, Melissa, Kutil, Zsófia, Bařinka, Cyril, Villagra, Alejandro, Kozikowski, Alan P.
I publikationen ACS Med Chem Lett (2017)

Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors

av Kutil, Zsófia, Mikešová, Jana, Zessin, Matthes, Meleshin, Marat, Nováková, Zora, Alquicer, Glenda, Kozikowski, Alan, Sippl, Wolfgang, Bařinka, Cyril, Schutkowski, Mike
I publikationen ACS Omega (2019)

Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening

av Temml, Veronika, Garscha, Ulrike, Romp, Erik, Schubert, Gregor, Gerstmeier, Jana, Kutil, Zsofia, Matuszczak, Barbara, Waltenberger, Birgit, Stuppner, Hermann, Werz, Oliver, Schuster, Daniela
I publikationen Sci Rep (2017)

The disordered N-terminus of HDAC6 is a microtubule-binding domain critical for efficient tubulin deacetylation

av Ustinova, Kseniya, Novakova, Zora, Saito, Makoto, Meleshin, Marat, Mikesova, Jana, Kutil, Zsofia, Baranova, Petra, Havlinova, Barbora, Schutkowski, Mike, Matthias, Patrick, Barinka, Cyril
I publikationen J Biol Chem (2020)

Human histone deacetylase 6 shows strong preference for tubulin dimers over assembled microtubules

av Skultetyova, Lubica, Ustinova, Kseniya, Kutil, Zsofia, Novakova, Zora, Pavlicek, Jiri, Mikesova, Jana, Trapl, Dalibor, Baranova, Petra, Havlinova, Barbora, Hubalek, Martin, Lansky, Zdenek, Barinka, Cyril
I publikationen Sci Rep (2017)

Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome

av Kozikowski, Alan P., Shen, Sida, Pardo, Marta, Tavares, Maurício T., Szarics, Dora, Benoy, Veronick, Zimprich, Chad A., Kutil, Zsófia, Zhang, Guiping, Bařinka, Cyril, Robers, Matthew B., Van Den Bosch, Ludo, Eubanks, James H., Jope, Richard S.
I publikationen ACS Chem Neurosci (2018)