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Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models

[Image: see text] Only a handful of therapies offer significant improvement in the overall survival in cases of melanoma, a cancer whose incidence has continued to rise in the past 30 years. In our effort to identify potent and isoform-selective histone deacetylase (HDAC) inhibitors as a therapeutic...

詳細記述

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書誌詳細
出版年:ACS Med Chem Lett
主要な著者: Tavares, Maurício T., Shen, Sida, Knox, Tessa, Hadley, Melissa, Kutil, Zsófia, Bařinka, Cyril, Villagra, Alejandro, Kozikowski, Alan P.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2017
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641951/
https://ncbi.nlm.nih.gov/pubmed/29057046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00223
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