Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors

[Image: see text] Histone deacetylase 11 (HDAC11) preferentially removes fatty acid residues from lysine side chains in a peptide or protein environment. Here, we report the development and validation of a continuous fluorescence-based activity assay using an internally quenched TNFα-derived peptide...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:ACS Omega
Huvudupphovsmän: Kutil, Zsófia, Mikešová, Jana, Zessin, Matthes, Meleshin, Marat, Nováková, Zora, Alquicer, Glenda, Kozikowski, Alan, Sippl, Wolfgang, Bařinka, Cyril, Schutkowski, Mike
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2019
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882135/
https://ncbi.nlm.nih.gov/pubmed/31788622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02808
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk