Targeting Energy Metabolism in Mycobacterium tuberculosis, a New Paradigm in Antimycobacterial Drug Discovery

著者: Bald, Dirk, Villellas, Cristina, Lu, Ping, Koul, Anil
出版年 mBio (2017)

Cloning and Characterization of Secretory Tyrosine Phosphatases of Mycobacterium tuberculosis

著者: Koul, Anil, Choidas, Axel, Treder, Martin, Tyagi, Anil K., Drlica, Karl, Singh, Yogendra, Ullrich, Axel
出版事項 2000

Probing the Interaction of the Diarylquinoline TMC207 with Its Target Mycobacterial ATP Synthase

著者: Haagsma, Anna C., Podasca, Ioana, Koul, Anil, Andries, Koen, Guillemont, Jerome, Lill, Holger, Bald, Dirk
出版事項 2011

Transcriptional Control of the Mycobacterial embCAB Operon by PknH through a Regulatory Protein, EmbR, In Vivo

著者: Sharma, Kirti, Gupta, Meetu, Pathak, Monika, Gupta, Nidhi, Koul, Anil, Sarangi, Smilona, Baweja, Renu, Singh, Yogendra
出版事項 2006

Role of Protein Kinase G in Growth and Glutamine Metabolism of Mycobacterium bovis BCG

著者: Nguyen, Liem, Walburger, Anne, Houben, Edith, Koul, Anil, Muller, Stefan, Morbitzer, Monika, Klebl, Bert, Ferrari, Giorgio, Pieters, Jean
出版事項 2005

Role of Protein Kinase G in Growth and Glutamine Metabolism of Mycobacterium bovis BCG

著者: Nguyen, Liem, Walburger, Anne, Houben, Edith, Koul, Anil, Muller, Stefan, Morbitzer, Monika, Klebl, Bert, Ferrari, Giorgio, Pieters, Jean
出版事項 2005

Structure of the mycobacterial ATP synthase F(o) rotor ring in complex with the anti-TB drug bedaquiline

著者: Preiss, Laura, Langer, Julian D., Yildiz, Özkan, Eckhardt-Strelau, Luise, Guillemont, Jérôme E. G., Koul, Anil, Meier, Thomas
出版年 Sci Adv (2015)

The cytochrome bd-type quinol oxidase is important for survival of Mycobacterium smegmatis under peroxide and antibiotic-induced stress

著者: Lu, Ping, Heineke, Marieke H., Koul, Anil, Andries, Koen, Cook, Gregory M., Lill, Holger, van Spanning, Rob, Bald, Dirk
出版年 Sci Rep (2015)

Acquired Resistance of Mycobacterium tuberculosis to Bedaquiline

著者: Andries, Koen, Villellas, Cristina, Coeck, Nele, Thys, Kim, Gevers, Tom, Vranckx, Luc, Lounis, Nacer, de Jong, Bouke C., Koul, Anil
出版事項 2014

Selectivity of TMC207 towards Mycobacterial ATP Synthase Compared with That towards the Eukaryotic Homologue

著者: Haagsma, Anna C., Abdillahi-Ibrahim, Rooda, Wagner, Marijke J., Krab, Klaas, Vergauwen, Karen, Guillemont, Jerome, Andries, Koen, Lill, Holger, Koul, Anil, Bald, Dirk
出版事項 2009

Pharmacokinetics-Pharmacodynamics of a Respiratory Syncytial Virus Fusion Inhibitor in the Cotton Rat Model

著者: Rouan, Marie-Claude, Gevers, Tom, Roymans, Dirk, de Zwart, Loeckie, Nauwelaers, David, De Meulder, Marc, van Remoortere, Pieter, Vanstockem, Marc, Koul, Anil, Simmen, Kenny, Andries, Koen
出版事項 2010

Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism

著者: Koul, Anil, Vranckx, Luc, Dhar, Neeraj, Göhlmann, Hinrich W.H., Özdemir, Emre, Neefs, Jean-Marc, Schulz, Melanie, Lu, Ping, Mørtz, Ejvind, McKinney, John D., Andries, Koen, Bald, Dirk
出版事項 2014

Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model

著者: Ispas, Gabriela, Koul, Anil, Verbeeck, Johan, Sheehan, Jennifer, Sanders-Beer, Brigitte, Roymans, Dirk, Andries, Koen, Rouan, Marie-Claude, De Jonghe, Sandra, Bonfanti, Jean-François, Vanstockem, Marc, Simmen, Kenneth, Verloes, Rene
出版年 PLoS One (2015)

Novel Antibiotics Targeting Respiratory ATP Synthesis in Gram-Positive Pathogenic Bacteria

著者: Balemans, Wendy, Vranckx, Luc, Lounis, Nacer, Pop, Ovidiu, Guillemont, Jérôme, Vergauwen, Karen, Mol, Selena, Gilissen, Ron, Motte, Magali, Lançois, David, De Bolle, Miguel, Bonroy, Kristien, Lill, Holger, Andries, Koen, Bald, Dirk, Koul, Anil
出版事項 2012

Molecular mechanism of respiratory syncytial virus fusion inhibitors

著者: Battles, Michael B, Langedijk, Johannes P, Furmanova-Hollenstein, Polina, Chaiwatpongsakorn, Supranee, Costello, Heather M, Kwanten, Leen, Vranckx, Luc, Vink, Paul, Jaensch, Steffen, Jonckers, Tim H M, Koul, Anil, Arnoult, Eric, Peeples, Mark E, Roymans, Dirk, McLellan, Jason S
出版年 Nat Chem Biol (2015)

Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region

著者: McGowan, David C., Balemans, Wendy, Embrechts, Werner, Motte, Magali, Keown, Jeremy R., Buyck, Christophe, Corbera, Jordi, Funes, Mario, Moreno, Laura, Cooymans, Ludwig, Tahri, Abdellah, Eymard, Julien, Stoops, Bart, Strijbos, Rudy, Van den Berg, Joke, Fodor, Ervin, Grimes, Jonathan M., Koul, Anil, Jonckers, Tim H.M., Raboisson, Pierre, Guillemont, Jérôme
出版年 J Med Chem (2019)

Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor

著者: Roymans, Dirk, Alnajjar, Sarhad S, Battles, Michael B, Sitthicharoenchai, Panchan, Furmanova-Hollenstein, Polina, Rigaux, Peter, Berg, Joke Van den, Kwanten, Leen, Ginderen, Marcia Van, Verheyen, Nick, Vranckx, Luc, Jaensch, Steffen, Arnoult, Eric, Voorzaat, Richard, Gallup, Jack M., Larios-Mora, Alejandro, Crabbe, Marjolein, Huntjens, Dymphy, Raboisson, Pierre, Langedijk, Johannes P., Ackermann, Mark R., McLellan, Jason S, Vendeville, Sandrine, Koul, Anil
出版年 Nat Commun (2017)