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Molecular mechanism of respiratory syncytial virus fusion inhibitors
Respiratory syncytial virus (RSV) is a leading cause of pneumonia and bronchiolitis in young children and the elderly. Therapeutic small molecules have been developed that bind the RSV F glycoprotein and inhibit membrane fusion, yet their binding sites and molecular mechanisms of action remain large...
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| Publicado no: | Nat Chem Biol |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731865/ https://ncbi.nlm.nih.gov/pubmed/26641933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1982 |
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