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Soluble Respiratory Syncytial Virus Fusion Protein in the Fully Cleaved, Pretriggered State Is Triggered by Exposure to Low-Molarity Buffer

The paramyxovirus fusion (F) glycoprotein is anchored in the virion membrane in a metastable, pretriggered form. Once triggered, the F protein undergoes a dramatic conformational extension that inserts its hydrophobic fusion peptide into the target cell membrane, then folds back on itself to bring t...

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Detalhes bibliográficos
Main Authors: Chaiwatpongsakorn, Supranee, Epand, Raquel F., Collins, Peter L., Epand, Richard M., Peeples, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126149/
https://ncbi.nlm.nih.gov/pubmed/21307202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01813-10
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