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Five Residues in the Apical Loop of the Respiratory Syncytial Virus Fusion Protein F(2) Subunit Are Critical for Its Fusion Activity

The respiratory syncytial virus (RSV) fusion (F) protein is a trimeric, membrane-anchored glycoprotein capable of mediating both virus-target cell membrane fusion to initiate infection and cell-cell fusion, even in the absence of the attachment glycoprotein. The F protein is initially expressed in a...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hicks, Stephanie N., Chaiwatpongsakorn, Supranee, Costello, Heather M., McLellan, Jason S., Ray, William, Peeples, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052300/
https://ncbi.nlm.nih.gov/pubmed/29743373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00621-18
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