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Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

Respiratory syncytial virus (RSV) invades host cells via a type I fusion (F) glycoprotein that undergoes dramatic structural rearrangements during the fusion process. Neutralizing monoclonal antibodies, such as 101F, palivizumab, and motavizumab, target two major antigenic sites on the RSV F glycopr...

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Autors principals: McLellan, Jason S., Yang, Yongping, Graham, Barney S., Kwong, Peter D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147929/
https://ncbi.nlm.nih.gov/pubmed/21613394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00555-11
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