Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F

Respiratory syncytial virus (RSV) is a major cause of pneumonia and bronchiolitis in infants and elderly people. Currently there is no effective vaccine against RSV, but passive prophylaxis with neutralizing antibodies reduces hospitalizations. To investigate the mechanism of antibody-mediated RSV n...

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Hlavní autoři: McLellan, Jason S., Chen, Man, Chang, Jung-San, Yang, Yongping, Kim, Albert, Graham, Barney S., Kwong, Peter D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976384/
https://ncbi.nlm.nih.gov/pubmed/20881049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01579-10
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