Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

The respiratory syncytial virus (RSV) fusion (F) glycoprotein prefusion conformation is the target of most RSV-neutralizing activity in human sera, but its metastability has hindered characterization. To overcome this obstacle, we identified prefusion-specific antibodies which were substantially mor...

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Dades bibliogràfiques
Publicat a:Science
Autors principals: McLellan, Jason S., Chen, Man, Leung, Sherman, Graepel, Kevin W., Du, Xiulian, Yang, Yongping, Zhou, Tongqing, Baxa, Ulrich, Yasuda, Etsuko, Beaumont, Tim, Kumar, Azad, Modjarrad, Kayvon, Zheng, Zizheng, Zhao, Min, Xia, Ningshao, Kwong, Peter D., Graham, Barney S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459498/
https://ncbi.nlm.nih.gov/pubmed/23618766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1234914
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