Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

The respiratory syncytial virus (RSV) fusion (F) glycoprotein prefusion conformation is the target of most RSV-neutralizing activity in human sera, but its metastability has hindered characterization. To overcome this obstacle, we identified prefusion-specific antibodies which were substantially mor...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: McLellan, Jason S., Chen, Man, Leung, Sherman, Graepel, Kevin W., Du, Xiulian, Yang, Yongping, Zhou, Tongqing, Baxa, Ulrich, Yasuda, Etsuko, Beaumont, Tim, Kumar, Azad, Modjarrad, Kayvon, Zheng, Zizheng, Zhao, Min, Xia, Ningshao, Kwong, Peter D., Graham, Barney S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459498/
https://ncbi.nlm.nih.gov/pubmed/23618766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1234914
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