Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein

Prevention efforts for respiratory syncytial virus (RSV) have been advanced due to the recent isolation and characterization of antibodies that specifically recognize the prefusion conformation of the RSV fusion (F) glycoprotein. These potently neutralizing antibodies are in clinical development for...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Gilman, Morgan S. A., Moin, Syed M., Mas, Vicente, Chen, Man, Patel, Nita K., Kramer, Kari, Zhu, Qing, Kabeche, Stephanie C., Kumar, Azad, Palomo, Concepción, Beaumont, Tim, Baxa, Ulrich, Ulbrandt, Nancy D., Melero, José A., Graham, Barney S., McLellan, Jason S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498696/
https://ncbi.nlm.nih.gov/pubmed/26161532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005035
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