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Structural basis of respiratory syncytial virus neutralization by motavizumab
Motavizumab is ~tenfold more potent than its predecessor, palivizumab (Synagis), the FDA-approved monoclonal antibody used to prevent respiratory syncytial virus (RSV) infection. The structure of motavizumab in complex with a 24-residue peptide corresponding to its epitope on the RSV fusion (F) glyc...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3050594/ https://ncbi.nlm.nih.gov/pubmed/20098425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1723 |
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