Novel Antibiotics Targeting Respiratory ATP Synthesis in Gram-Positive Pathogenic Bacteria

Emergence of drug-resistant bacteria represents a high, unmet medical need, and discovery of new antibacterials acting on new bacterial targets is strongly needed. ATP synthase has been validated as an antibacterial target in Mycobacterium tuberculosis, where its activity can be specifically blocked...

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Autori principali: Balemans, Wendy, Vranckx, Luc, Lounis, Nacer, Pop, Ovidiu, Guillemont, Jérôme, Vergauwen, Karen, Mol, Selena, Gilissen, Ron, Motte, Magali, Lançois, David, De Bolle, Miguel, Bonroy, Kristien, Lill, Holger, Andries, Koen, Bald, Dirk, Koul, Anil
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Mechanisms of Action: Physiological Effects
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421580/
https://ncbi.nlm.nih.gov/pubmed/22615276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00273-12
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