Novel Antibiotics Targeting Respiratory ATP Synthesis in Gram-Positive Pathogenic Bacteria

Emergence of drug-resistant bacteria represents a high, unmet medical need, and discovery of new antibacterials acting on new bacterial targets is strongly needed. ATP synthase has been validated as an antibacterial target in Mycobacterium tuberculosis, where its activity can be specifically blocked...

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Detalhes bibliográficos
Main Authors: Balemans, Wendy, Vranckx, Luc, Lounis, Nacer, Pop, Ovidiu, Guillemont, Jérôme, Vergauwen, Karen, Mol, Selena, Gilissen, Ron, Motte, Magali, Lançois, David, De Bolle, Miguel, Bonroy, Kristien, Lill, Holger, Andries, Koen, Bald, Dirk, Koul, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421580/
https://ncbi.nlm.nih.gov/pubmed/22615276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00273-12
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