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Bactericidal Potencies of New Regimens Are Not Predictive of Their Sterilizing Potencies in a Murine Model of Tuberculosis

TMC207, rifapentine, and moxifloxacin are in clinical testing for the treatment of tuberculosis. Five experimental regimens with various combinations of TMC207, rifapentine, moxifloxacin, and pyrazinamide were tested for their bactericidal and sterilizing potencies in Swiss mice intravenously inocul...

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Bibliografische gegevens
Hoofdauteurs: Andries, Koen, Gevers, Tom, Lounis, Nacer
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976132/
https://ncbi.nlm.nih.gov/pubmed/20713662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00934-10
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