Sterilizing Activity of Second-Line Regimens Containing TMC207 in a Murine Model of Tuberculosis

RATIONALE: The sterilizing activity of the regimen used to treat multidrug resistant tuberculosis (MDR TB) has not been studied in a mouse model. OBJECTIVE AND METHODS: Swiss mice were intravenously inoculated with 6 log10 of Mycobacterium tuberculosis (TB) strain H37Rv, treated with second-line dru...

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Détails bibliographiques
Auteurs principaux: Veziris, Nicolas, Ibrahim, Murad, Lounis, Nacer, Andries, Koen, Jarlier, Vincent
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048299/
https://ncbi.nlm.nih.gov/pubmed/21408613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017556
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