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Sterilizing Activity of Second-Line Regimens Containing TMC207 in a Murine Model of Tuberculosis
RATIONALE: The sterilizing activity of the regimen used to treat multidrug resistant tuberculosis (MDR TB) has not been studied in a mouse model. OBJECTIVE AND METHODS: Swiss mice were intravenously inoculated with 6 log10 of Mycobacterium tuberculosis (TB) strain H37Rv, treated with second-line dru...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048299/ https://ncbi.nlm.nih.gov/pubmed/21408613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017556 |
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