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Bactericidal Potencies of New Regimens Are Not Predictive of Their Sterilizing Potencies in a Murine Model of Tuberculosis

TMC207, rifapentine, and moxifloxacin are in clinical testing for the treatment of tuberculosis. Five experimental regimens with various combinations of TMC207, rifapentine, moxifloxacin, and pyrazinamide were tested for their bactericidal and sterilizing potencies in Swiss mice intravenously inocul...

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Detalhes bibliográficos
Main Authors: Andries, Koen, Gevers, Tom, Lounis, Nacer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976132/
https://ncbi.nlm.nih.gov/pubmed/20713662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00934-10
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