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Impact of the Interaction of R207910 with Rifampin on the Treatment of Tuberculosis Studied in the Mouse Model

New drugs are needed to shorten the duration of tuberculosis treatment. R207910, a diarylquinoline, is very active against Mycobacterium tuberculosis both in vitro and in mice. In healthy volunteers, the coadministration of R207910 and rifampin induced the increased metabolism of R207910, resulting...

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Bibliografski detalji
Glavni autori: Lounis, Nacer, Gevers, Tom, Van Den Berg, Joke, Andries, Koen
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565917/
https://ncbi.nlm.nih.gov/pubmed/18644960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00566-08
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