Candida albicans Morphogenesis Is Not Required for Macrophage Interleukin 1β Production

Por Wellington, Melanie, Koselny, Kristy, Krysan, Damian J.
Publicado em 2012

Candida albicans Triggers NLRP3-Mediated Pyroptosis in Macrophages

Por Wellington, Melanie, Koselny, Kristy, Sutterwala, Fayyaz S., Krysan, Damian J.
Publicado em 2014

A Genome-Wide Screen of Deletion Mutants in the Filamentous Saccharomyces cerevisiae Background Identifies Ergosterol as a Direct Trigger of Macrophage Pyroptosis

Por Koselny, Kristy, Mutlu, Nebibe, Minard, Annabel Y., Kumar, Anuj, Krysan, Damian J., Wellington, Melanie
Publicado no mBio (2018)

Cryptococcus neoformans Phosphoinositide-Dependent Kinase 1 (PDK1) Ortholog Is Required for Stress Tolerance and Survival in Murine Phagocytes

Por Chabrier-Roselló, Yeissa, Gerik, Kimberly J., Koselny, Kristy, DiDone, Louis, Lodge, Jennifer K., Krysan, Damian J.
Publicado em 2013

Antitumor/Antifungal Celecoxib Derivative AR-12 is a Non-Nucleoside Inhibitor of the ANL-Family Adenylating Enzyme Acetyl CoA Synthetase

Por Koselny, Kristy, Green, Julianne, Favazzo, Lacey, Glazier, Virginia E., DiDone, Louis, Ransford, Shea, Krysan, Damian J.
Publicado no ACS Infect Dis (2016)

A Repurposing Approach Identifies Off-Patent Drugs with Fungicidal Cryptococcal Activity, a Common Structural Chemotype, and Pharmacological Properties Relevant to the Treatment of...

Por Butts, Arielle, DiDone, Louis, Koselny, Kristy, Baxter, Bonnie K., Chabrier-Rosello, Yeissa, Wellington, Melanie, Krysan, Damian J.
Publicado em 2013

Genetic analysis of the Candida albicans biofilm transcription factor network using simple and complex haploinsufficiency

Por Glazier, Virginia E., Murante, Thomas, Murante, Daniel, Koselny, Kristy, Liu, Yuan, Kim, Dongyeop, Koo, Hyun, Krysan, Damian J.
Publicado no PLoS Genet (2017)

Systematic Complex Haploinsufficiency-Based Genetic Analysis of Candida albicans Transcription Factors: Tools and Applications to Virulence-Associated Phenotypes

Por Glazier, Virginia E., Murante, Thomas, Koselny, Kristy, Murante, Daniel, Esqueda, Marisol, Wall, Gina A., Wellington, Melanie, Hung, Chiung-Yu, Kumar, Anuj, Krysan, Damian J.
Publicado no G3 (Bethesda) (2018)

The Spx Regulator Modulates Stress Responses and Virulence in Enterococcus faecalis

Por Kajfasz, Jessica K., Mendoza, Jorge E., Gaca, Anthony O., Miller, James H., Koselny, Kristy A., Giambiagi-deMarval, Marcia, Wellington, Melanie, Abranches, Jacqueline, Lemos, José A.
Publicado em 2012

The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis

Por Koselny, Kristy, Green, Julianne, DiDone, Louis, Halterman, Justin P., Fothergill, Annette W., Wiederhold, Nathan P., Patterson, Thomas F., Cushion, Melanie T., Rappelye, Chad, Wellington, Melanie, Krysan, Damian J.
Publicado no Antimicrob Agents Chemother (2016)

Estrogen Receptor Antagonists Are Anti-Cryptococcal Agents That Directly Bind EF Hand Proteins and Synergize with Fluconazole In Vivo

Por Butts, Arielle, Koselny, Kristy, Chabrier-Roselló, Yeissa, Semighini, Camile P., Brown, Jessica C. S., Wang, Xuying, Annadurai, Sivakumar, DiDone, Louis, Tabroff, Julie, Childers, Wayne E., Abou-Gharbia, Magid, Wellington, Melanie, Cardenas, Maria E., Madhani, Hiten D., Heitman, Joseph, Krysan, Damian J.
Publicado em 2014

High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis

Por O’Meara, Teresa R., Duah, Kwamaa, Guo, Cynthia X., Maxson, Michelle E., Gaudet, Ryan G., Koselny, Kristy, Wellington, Melanie, Powers, Michael E., MacAlpine, Jessie, O’Meara, Matthew J., Veri, Amanda O., Grinstein, Sergio, Noble, Suzanne M., Krysan, Damian, Gray-Owen, Scott D., Cowen, Leah E.
Publicado no mBio (2018)