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High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis

The innate immune system is the first line of defense against invasive fungal infections. As a consequence, many successful fungal pathogens have evolved elegant strategies to interact with host immune cells. For example, Candida albicans undergoes a morphogenetic switch coupled to cell wall remodel...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: O’Meara, Teresa R., Duah, Kwamaa, Guo, Cynthia X., Maxson, Michelle E., Gaudet, Ryan G., Koselny, Kristy, Wellington, Melanie, Powers, Michael E., MacAlpine, Jessie, O’Meara, Matthew J., Veri, Amanda O., Grinstein, Sergio, Noble, Suzanne M., Krysan, Damian, Gray-Owen, Scott D., Cowen, Leah E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6106084/
https://ncbi.nlm.nih.gov/pubmed/30131363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01581-18
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