High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis

The innate immune system is the first line of defense against invasive fungal infections. As a consequence, many successful fungal pathogens have evolved elegant strategies to interact with host immune cells. For example, Candida albicans undergoes a morphogenetic switch coupled to cell wall remodel...

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Vydáno v:mBio
Hlavní autoři: O’Meara, Teresa R., Duah, Kwamaa, Guo, Cynthia X., Maxson, Michelle E., Gaudet, Ryan G., Koselny, Kristy, Wellington, Melanie, Powers, Michael E., MacAlpine, Jessie, O’Meara, Matthew J., Veri, Amanda O., Grinstein, Sergio, Noble, Suzanne M., Krysan, Damian, Gray-Owen, Scott D., Cowen, Leah E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6106084/
https://ncbi.nlm.nih.gov/pubmed/30131363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01581-18
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