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Candida albicans Triggers NLRP3-Mediated Pyroptosis in Macrophages

Pyroptosis is an inflammasome-mediated programmed cell death pathway triggered in macrophages by a variety of stimuli, including intracellular bacterial pathogens. Activation of pyroptosis leads to the secretion of interleukin-1β (IL-1β) and pore-mediated cell lysis. Although not considered an intra...

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Detalhes bibliográficos
Main Authors: Wellington, Melanie, Koselny, Kristy, Sutterwala, Fayyaz S., Krysan, Damian J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910967/
https://ncbi.nlm.nih.gov/pubmed/24376002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00336-13
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