Impact of Zinc Metabolism on Innate Immune Function in the Setting of Sepsis

Por Knoell, Daren L., Liu, Ming-Jie
Publicado em 2010

Sepsis: Links between Pathogen Sensing and Organ Damage

Por Crouser, Elliott, Exline, Matthew, Knoell, Daren, Wewers, Mark D.
Publicado em 2008

Alveolar Epithelial Cells in Mycobacterium tuberculosis Infection: Active Players or Innocent Bystanders?

Por Scordo, Julia M., Knoell, Daren L., Torrelles, Jordi B.
Publicado no J Innate Immun (2016)

A Genotyping Exercise for Pharmacogenetics in Pharmacy Practice

Por Knoell, Daren L., Johnston, Jeffrey S., Bao, Shengying, Kelley, Katherine A.
Publicado em 2009

Inhibition of the phosphatase PTEN protects mice against oleic acid-induced acute lung injury

Por Lai, Ju-Ping, Bao, Shengying, Davis, Ian C, Knoell, Daren L
Publicado em 2009

PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration

Por Mihai, Cosmin, Bao, Shengying, Lai, Ju-Ping, Ghadiali, Samir N., Knoell, Daren L.
Publicado em 2012

Tissue-Specific Induction of Mouse ZIP8 and ZIP14 Divalent Cation/Bicarbonate Symporters by, and Cytokine Response to, Inflammatory Signals

Por Gálvez-Peralta, Marina, Wang, Zhifang, Bao, Shengying, Knoell, Daren L, Nebert, Daniel W
Publicado em 2014

Allelic mRNA expression imbalance in C-type lectins reveals a frequent regulatory SNP in the human surfactant protein A (SP-A) gene

Por Azad, Abul K., Curtis, Amanda, Papp, Audrey, Webb, Amy, Knoell, Daren, Sadee, Wolfgang, Schlesinger, Larry S.
Publicado em 2013

Intestinal epithelium is more susceptible to cytopathic injury and altered permeability than the lung epithelium in the context of acute sepsis

Por Julian, Mark W, Bao, Shengying, Knoell, Daren L, Fahy, Ruairi J, Shao, Guohong, Crouser, Elliott D
Publicado em 2011

Cadmium attenuates the macrophage response to LPS through inhibition of the NF-κB pathway

Por Cox, Jessica Napolitano, Rahman, Mohd. Akhlakur, Bao, Shengying, Liu, Mingjie, Wheeler, Sarah E., Knoell, Daren L.
Publicado no Am J Physiol Lung Cell Mol Physiol (2016)

Zinc Modulates Endotoxin-Induced Human Macrophage Inflammation through ZIP8 Induction and C/EBPβ Inhibition

Por Pyle, Charlie J., Akhter, Saife, Bao, ShengYing, Dodd, Claire E., Schlesinger, Larry S., Knoell, Daren L.
Publicado no PLoS One (2017)

Elemental Ingredients in the Macrophage Cocktail: Role of ZIP8 in Host Response to Mycobacterium tuberculosis

Por Pyle, Charlie J., Azad, Abul K., Papp, Audrey C., Sadee, Wolfgang, Knoell, Daren L., Schlesinger, Larry S.
Publicado no Int J Mol Sci (2017)

TGF-β1 stimulates human AT(1) receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways

Por Martin, Mickey M., Buckenberger, Jessica A., Jiang, Jinmai, Malana, Geraldine E., Knoell, Daren L., Feldman, David S., Elton, Terry S.
Publicado em 2007

Zinc modulates the innate immune response in vivo to polymicrobial sepsis through regulation of NF-κB

Por Bao, Shengying, Liu, Ming-Jie, Lee, Bryan, Besecker, Beth, Lai, Ju-Ping, Guttridge, Denis C., Knoell, Daren L.
Publicado em 2010

Zinc Regulates the Acute Phase Response and Serum Amyloid A Production in Response to Sepsis through JAK-STAT3 Signaling

Por Liu, Ming-Jie, Bao, Shengying, Napolitano, Jessica R., Burris, Dara L., Yu, Lianbo, Tridandapani, Susheela, Knoell, Daren L.
Publicado em 2014

Cadmium-mediated toxicity of lung epithelia is enhanced through NF-κB-mediated transcriptional activation of the human zinc transporter ZIP8

Por Napolitano, Jessica R., Liu, Ming-Jie, Bao, Shengying, Crawford, Melissa, Nana-Sinkam, Patrick, Cormet-Boyaka, Estelle, Knoell, Daren L.
Publicado em 2012

IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae

Por Sundaram, Kruthika, Rahman, Mohd. Akhlakur, Mitra, Srabani, Knoell, Daren L., Woodiga, Shireen A., King, Samantha J., Wewers, Mark D.
Publicado no PLoS One (2016)

A comparison of zinc metabolism, inflammation, and disease severity in critically ill infected and noninfected adults early after intensive care unit admission(1)(2)(3)

Por Besecker, Beth Y, Exline, Matthew C, Hollyfield, Jennifer, Phillips, Gary, DiSilvestro, Robert A, Wewers, Mark D, Knoell, Daren L
Publicado em 2011

Formyl Peptide Receptor Ligands Promote Wound Closure in Lung Epithelial Cells

Por Shao, Guohong, Julian, Mark W., Bao, Shengying, McCullers, Meghan K., Lai, Ju-Ping, Knoell, Daren L., Crouser, Elliott D.
Publicado em 2011

Mitochondrial Transcription Factor A (TFAM) Serves as a Danger Signal by Augmenting Plasmacytoid Dendritic Cell Responses to DNA()

Por Julian, Mark W., Shao, Guohong, Bao, Shengying, Knoell, Daren L., Papenfuss, Tracey L., VanGundy, Zachary C., Crouser, Elliott D.
Publicado em 2012