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Inhibition of the phosphatase PTEN protects mice against oleic acid-induced acute lung injury

BACKGROUND AND PURPOSE: Injury to the lung parenchyma is a constitutional feature shared by many lung diseases. The protein, phosphatase and tensin homologue deleted on chromosome Ten (PTEN) is a major suppressor of phosphoinositide-3 kinase/Akt signalling, a vital survival pathway in lung parenchym...

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Bibliografiset tiedot
Päätekijät: Lai, Ju-Ping, Bao, Shengying, Davis, Ian C, Knoell, Daren L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697782/
https://ncbi.nlm.nih.gov/pubmed/19134000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00020.x
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