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PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration

The phosphoinositide-3 kinase/Akt pathway is a vital survival axis in lung epithelia. We previously reported that inhibition of phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a major suppressor of this pathway, results in enhanced wound repair following injury. However, the precise...

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Bibliografski detalji
Glavni autori: Mihai, Cosmin, Bao, Shengying, Lai, Ju-Ping, Ghadiali, Samir N., Knoell, Daren L.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289272/
https://ncbi.nlm.nih.gov/pubmed/22037358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00037.2011
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