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PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration
The phosphoinositide-3 kinase/Akt pathway is a vital survival axis in lung epithelia. We previously reported that inhibition of phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a major suppressor of this pathway, results in enhanced wound repair following injury. However, the precise...
Tallennettuna:
| Päätekijät: | , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Physiological Society
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289272/ https://ncbi.nlm.nih.gov/pubmed/22037358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00037.2011 |
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