TGF-β1 stimulates human AT(1) receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways

Both angiotensin II (ANG II) and transforming growth factor-β1 (TGF-β1) are thought to be involved in mediating pulmonary fibrosis. Interactions between the renin-angiotensin system (RAS) and TGF-β1 have been well documented, with most studies describing the effect of ANG II on TGF-β1 expression. Ho...

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Detalhes bibliográficos
Main Authors: Martin, Mickey M., Buckenberger, Jessica A., Jiang, Jinmai, Malana, Geraldine E., Knoell, Daren L., Feldman, David S., Elton, Terry S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413071/
https://ncbi.nlm.nih.gov/pubmed/17601799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00099.2007
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