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TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-β
In many physiological and disease processes, TGF-β usurps branches of MAP kinase pathways in conjunction to Smads to induce apoptosis and epithelial to mesenchymal transition, but the detailed mechanism of how a MAP kinase cascade is activated by TGF-β receptors is not clear. We report here that TRA...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2621323/ https://ncbi.nlm.nih.gov/pubmed/18922473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.09.002 |
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