The Human Angiotensin II Type 1 Receptor + 1166 A/C Polymorphism Attenuates MicroRNA-155 Binding

The adverse effects of angiotensin II (Ang II) are primarily mediated through the Ang II type 1 receptor (AT(1)R). A silent polymorphism (+1166 A/C) in the human AT(1)R gene has been associated with cardiovascular disease, possibly as a result of enhanced AT(1)R activity. Because this polymorphism o...

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Main Authors: Martin, Mickey M., Buckenberger, Jessica A., Jiang, Jinmai, Malana, Geraldine E., Nuovo, Gerard J., Chotani, Maqsood, Feldman, David S., Schmittgen, Thomas D., Elton, Terry S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413065/
https://ncbi.nlm.nih.gov/pubmed/17588946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701050200
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