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The Human Angiotensin II Type 1 Receptor + 1166 A/C Polymorphism Attenuates MicroRNA-155 Binding
The adverse effects of angiotensin II (Ang II) are primarily mediated through the Ang II type 1 receptor (AT(1)R). A silent polymorphism (+1166 A/C) in the human AT(1)R gene has been associated with cardiovascular disease, possibly as a result of enhanced AT(1)R activity. Because this polymorphism o...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2413065/ https://ncbi.nlm.nih.gov/pubmed/17588946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701050200 |
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