Human Chromosome 21-derived miRNAs are Over-expressed in Down Syndrome Brains and Hearts

Down syndrome (DS), or Trisomy 21, is the most common genetic cause of cognitive impairment and congenital heart defects in the human population. To date, the contribution of microRNAs (miRNAs) in DS has not been investigated. Bioinformatic analyses demonstrate that human chromosome 21 (Hsa21) harbo...

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Detalhes bibliográficos
Main Authors: Kuhn, Donald E., Nuovo, Gerard J., Martin, Mickey M., Malana, Geraldine E., Pleister, Adam P., Jiang, Jinmai, Schmittgen, Thomas D., Terry, Alvin V., Gardiner, Katheleen, Head, Elizabeth, Feldman, David S., Elton, Terry S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585520/
https://ncbi.nlm.nih.gov/pubmed/18387358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.03.120
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